RESEARCH PAPERS: Solid/Liquid Phase Change

Microscale Heat and Mass Transfer of Vascular and Intracellular Freezing in the Liver

[+] Author and Article Information
J. C. Bischof

Massachusetts General Hospital, Surgical Research Labs, Charlestown, MA 02129

B. Rubinsky

University of California at Berkeley, Department of Mechanical Engineering, Berkeley, CA 94720

J. Heat Transfer 115(4), 1029-1035 (Nov 01, 1993) (7 pages) doi:10.1115/1.2911357 History: Received July 01, 1992; Revised January 01, 1993; Online May 23, 2008


A set of heat and mass transfer equations is developed to predict vascular as well as intracellular ice formation during freezing in liver tissue. A modified Krogh unit with vascular and cellular compartments is used. In the model intracellular ice formation is predicted by a probability integral with functional dependence on cell compartment volume, temperature, and time. Finite difference computer simulations qualitatively predict the amount and location of vascular and intracellular ice, the temperature distribution in the tissue, and the position of the partial and total freezing interfaces at any time.

Copyright © 1993 by The American Society of Mechanical Engineers
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