This article describes the peristaltic transport of nanofluids in a curved channel. Transport equations contain the simultaneous effects of Brownian motion and thermophoretic diffusion of nanoparticles. The governing equations are modeled. Mathematical analysis is performed subject to long wavelength and low Reynolds number assumptions. Numerical solutions are obtained by employing shooting method. Results indicate an increase in the pumping rate when the strengths of Brownian motion and thermophoresis effects are increased. It is observed that the profiles of temperature and nanoparticles concentration are not symmetric about the central line of the curved channel which is different from the case of planar channel.