The main goal of this paper is to analyze the thermal and hydrodynamic behaviors of laminar mixed convection flow of a nongray radiating gas over an inclined step in an inclined duct. The fluid is considered an air mixture with 10% CO2 and 20% H2O mole fractions, which is treated as homogeneous, absorbing, emitting, and nonscattering medium. The full-spectrum k-distribution (FSK) method is used to handle the nongray part of the problem, while the radiative transfer equation (RTE) is solved using the discrete ordinate method (DOM). In addition, the results are obtained for different medium assumptions such as pure mixed convection and gray medium to compare with the nongray calculations as a real case. The results show that in many cases, neglecting the radiation part in computations and also use of gray simulations are not acceptable and lead to considerable errors, especially at high values of the Grashof number in mixed convection flow.