This paper reports the numerical results for the natural convection flow of a two-phase dusty nanofluid along a vertical wavy frustum of a cone. The general governing equations are transformed into parabolic partial differential equations, which are then solved numerically with the help of implicit finite difference method. Comprehensive flow formations of carrier and dusty phases are given with the aim to predict the behavior of heat and mass transport across the heated wavy frustum of a cone. The effectiveness of utilizing the nanofluids to control skin friction and heat and mass transport is analyzed. The results clearly show that the shape of the waviness changes when nanofluid is considered. It is shown that the modified diffusivity ratio parameter, NA, extensively promotes rate of mass transfer near the vicinity of the cone, whereas heat transfer rate reduces.