This work studies numerically the combined heat and mass transfer of uniform blowing/suction, non-Newtonian power-law fluid, and thermal radiation effects on free convection adjacent to a vertical cone within a porous medium in the presence of Soret/Dufour effects. The surface of the vertical cone has a uniform wall temperature and uniform wall concentration (UWT/UWC). The Rosseland diffusion approximation is employed to describe the radiative heat flux. A nonsimilarity analysis is performed, and the transformed governing equations are solved by Keller box method (KBM). The effects of these major parameters of the Dufour parameter, Soret parameter, Lewis number, buoyancy ratio, power-law index of the non-Newtonian fluids, blowing/suction parameter, and thermal radiation parameter on the heat and mass transfer characteristics have been carried out. In general, for the case of blowing, both the local Nusselt number and the local Sherwood number decrease. This trend reversed for suction of fluid. The physical aspects of the problem are discussed in detail.