A study on the constitutive models of tumor tissues is critical for the advancement of computational tools for clinical diagnosis and treatment plans. In this respect, continuum based constitutive models of tumor tissues applied in the computational analysis of tumor tissues are reviewed in this work. An introduction to the continuum based computational modeling of tumor tissue and a brief review of the applications of computational models in tumor diagnosis and treatment plans are presented in Sec. 1. The pathophysiology of tumor is given in Sec. 2. Continuum based constitutive models of tumor tissues are reviewed in Sec. 3 and in Sec. 4, conclusions and recommendations for the future development of tumor constitutive model are presented. It is the aim of the authors to provide a comprehensive study on the various constitutive models of tumors to enhance the application of biomechanical simulation of tumor tissues.
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July 2010
Review Articles
Review on the Constitutive Models of Tumor Tissue for Computational Analysis
G. U. Unnikrishnan,
G. U. Unnikrishnan
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
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V. U. Unnikrishnan,
V. U. Unnikrishnan
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
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J. N. Reddy,
J. N. Reddy
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
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C. T. Lim
C. T. Lim
Division of Bioengineering,
National University of Singapore
, 9 Engineering Drive 1, Singapore 117576, Singapore
Search for other works by this author on:
G. U. Unnikrishnan
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
V. U. Unnikrishnan
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
J. N. Reddy
Department of Mechanical Engineering, Advanced Computational Mechanics Laboratory,
Texas A&M University
, College Station, TX 77843-3123
C. T. Lim
Division of Bioengineering,
National University of Singapore
, 9 Engineering Drive 1, Singapore 117576, SingaporeAppl. Mech. Rev. Jul 2010, 63(4): 040801 (7 pages)
Published Online: October 27, 2010
Article history
Received:
April 7, 2010
Revised:
August 3, 2010
Online:
October 27, 2010
Published:
October 27, 2010
Citation
Unnikrishnan, G. U., Unnikrishnan, V. U., Reddy, J. N., and Lim, C. T. (October 27, 2010). "Review on the Constitutive Models of Tumor Tissue for Computational Analysis." ASME. Appl. Mech. Rev. July 2010; 63(4): 040801. https://doi.org/10.1115/1.4002427
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