Abstract
A method has been developed for the analysis of psilocybin and psilocin in dry and preserved mushrooms using reversed-phase high performance liquid chromatography. A mobile phase of phosphate buffered methanol/water/cetrimonium bromide allows good separation of the two hallucinogens.
Issue Section:
Research Papers
References
1.
Hofmann
, A.
, Heim
, R.
, Brack
, A.
, and Kobel
, H.
, “Psilocybin, ein psychotroper Wirkstoff aus dem mexikanischen rauschpilz Psilocybe mexicana Heim
,” Experientia
, Vol. 14
, 1958
, pp. 107
–109
.2.
Heim
, R.
, Genest
, K.
, Hughes
, D. W.
, and Belec
, G.
, “Botanical and Chemical Characterisation of a Forensic Mushroom Specimen of the Genus Psilocybe
,” Forensic Science Society Journal
, Vol. 6
, 1966
, pp. 192
–201
.3.
Aboul-Enein
, H. Y.
, “Psilocybin: a Pharmacological Profile
,” American Journal of Pharmacy
, Vol. 146
, No. 3
, May–June 1974, pp. 91
–95
.4.
Hofmann
, A.
, Frey
, A.
, Ott
, H.
, Petrzilka
, Th.
, and Troxler
, F.
, “Konstitionsaufklarung und Synthese von Psilocybin
,” Experientia
, Vol. 14
, 1958
, pp. 397
–399
.5.
Mesley
, R. J.
and Evans
, W. H.
, “Infrared Identification of Some Hallucinogenic Derivatives of Tryptamine and Amphetamine
,” Journal of Pharmacy and Pharmacology
, Vol. 22
, 1970
, pp. 321
–332
.6.
Repke
, D. B.
, Leslie
, D. T.
, Mandell
, D. M.
, and Kish
, N. G.
, “GLC-Mass Spectral Analysis of Psilocin and Psilocybin
,” Journal of Pharmaceutical Sciences
, Vol. 66
, No. 5
, 05
1977
, pp. 743
–744
.7.
White
, P. C.
, “Analysis of Extracts from Psilocybe semilanceata Mushrooms by High-Pressure Liquid Chromatography
,” Journal of Chromatography
0021-9673, Vol. 169
, 02
1979
, pp. 453
–456
.8.
Parris
, N. A.
, Journal of Chromatography Library. Vol. 5. Instrumental Liquid Chromatography
, Elsevier
, Amsterdam
, 1976
.9.
Eksborg
, S.
and Schill
, G.
, “Ion Pair Partition Chromatography of Organic Ammonium Compounds
,” Analytical Chemistry
0003-2700, Vol. 45
, No. 12
, 10
1973
, pp. 2092
–2100
.10.
Eksborg
, S.
, Lagerström
, P.
, Modin
, R.
, and Schill
, G.
, “Ion-Pair Chromatography of Organic Compounds
,” Journal of Chromatography
0021-9673, Vol. 83
, 1973
, pp. 99
–110
.11.
Knox
, J. H.
and Laird
, G. R.
, “Soap Chromatography—A New High-Performance Liquid Chromatographic Technique for Separation of Ionizable Materials, Dyestuff Intermediates
,” Journal of Chromatography
0021-9673, Vol. 122
, 1976
, pp. 17
–34
.12.
Chudy
, J.
, Crosby
, N. T.
, and Patel
, I.
, “Separation of Synthetic Food Dyes Using High-Performance Liquid Chromatography
,” Journal of Chromatography
0021-9673, Vol. 154
, No. 2
, 07
1978
, pp. 306
–312
.13.
Tomlinson
, E.
, Riley
, C. M.
, and Jefferies
, T. M.
, “Ion-Pair High-Performance Liquid Chromatography: The Use of Low Concentrations of Long-Chain Alkylbenzyldimethylammonium Chlorides for Resolving Anionic Solutes
,” Journal of Chromatography
0021-9673, Vol. 173
, No. 1
, 05
1979
, pp. 89
–100
.14.
Gloor
, R.
and Johnson
, E. L.
,. “Practical Aspects of Reverse Phase Ion Pair Chromatography
,” Journal of Chromatographic Science
, Vol. 15
, No. 9
, 09
1977
, pp. 413
–423
.15.
Walton
, H. F.
, “Ion Exchange and Liquid Column Chromatography
,” Analytical Chemistry
0003-2700, Vol. 50
, No. 5
, 04
1978
, pp. 36R
–50R
.16.
Kissinger
, P. T.
, “Comments on Reverse-Phase Ion-Pair Partition Chromatography
,” Analytical Chemistry
0003-2700, Vol. 49
, No. 6
, 05
1977
, p. 883.
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