...AM Baker, MD; DG Johnson, MD; JA Levisky, MS; WL Hearn, PhD; KA Moore, PhD; B Levine, PhD; SJ Nelson, MA Diphenhydramine is an antihistamine available in numerous over-the-counter preparations. Often used for its sedative effects in adults, it can cause paradoxical central nervous system...

... are unavailable. In the present study, the concentrations of six drugs (bromisovalum, ephedrine, hydroxyzine, diphenhydramine, ranitidine, and lidocaine) and a metabolite of lidocaine (glycinexylidide) were determined using both methods. The slopes of the regression lines between the rapid estimate method...