In vivo measurement of loads and pressures acting on articular cartilage in the knee joint during various activities and rehabilitative therapies following focal defect repair will provide a means of designing activities that encourage faster and more complete healing of focal defects. It was the goal of this study to develop a totally portable monitoring system that could be used during various activities and allow continuous monitoring of forces acting on the knee. In order to make the monitoring system portable, a handheld computer with custom software, a USB powered miniature wireless receiver, and a battery-powered coil were developed to replace a currently used computer, ac powered benchtop receiver, and power supply. A Dell handheld running Windows Mobile operating system programed using LABVIEW was used to collect strain measurements. Measurements collected by the handheld-based system connected to the miniature wireless receiver were compared with the measurements collected by a hardwired system and a computer based system during benchtop testing and in vivo testing. The newly developed handheld-based system had a maximum accuracy of 99% when compared to the computer based system.

1.
Brand
,
R. A.
,
Pedersen
,
D. R.
,
Davy
,
D. T.
,
Kotzar
,
G. M.
,
Heiple
,
K. G.
, and
Goldberg
,
V. M.
, 1994, “
Comparison of hip Force Calculations and Measurements in the Same Patient
,”
J. Arthroplasty
0883-5403,
9
(
1
), pp.
45
51
.
2.
Komistek
,
R. D.
,
Stiehl
,
J. B.
, and
Dennis
,
D. A.
, 1998, “
Mathematical Model of the Lower Extremity Joint Reaction Forces Using Kane’s Method of Dynamics
,”
J. Biomech.
0021-9290,
31
, pp.
185
189
.
3.
Komistek
,
R. D.
,
Dennis
,
D. A.
,
Mabe
,
J. A.
, and
Walker
,
S. A.
, 2000, “
In Vivo Determination of Patellofemoral Contact Positions
,”
Clinical Biomechanics
,
15
(
1
), pp.
29
36
.
4.
Lutz
,
G. E.
,
Palmitier
,
R. A.
,
An
,
K. N.
, and
Chao
,
E. Y.
, 1993, “
Comparison of Tibiofemoral Joint Forces During Open-Kinetic-Chain and Closed Kinetic-Chain Exercises
,”
J. Bone Jt. Surg., Am. Vol.
0021-9355,
75A
, pp.
732
739
.
5.
Nisell
,
R.
,
Ericson
,
M. O.
,
Nemeth
,
G.
, and
Ekholm
,
J.
, 1989, “
Tibiofemoral Joint Forces During Isokinetic Knee Extension
,”
Am. J. Sports Med.
0363-5465,
17
, pp.
49
54
.
6.
Seireg
,
A.
, and
Arvikar
,
R. J.
, 1973, “
The Prediction of Muscular Load Sharing and Joint Forces in the Lower Extremities During Walking
,”
J. Biomech.
0021-9290,
8
, pp.
89
102
.
7.
Seireg
,
A.
, and
Avikar
,
R. J.
, 1973, “
A Mathematical Model for Evaluation of Forces in Lower Extremeties of the Musculo-Skeletal System
,”
J. Biomech.
0021-9290,
6
, pp.
313
326
.
8.
Davy
,
D. T.
,
Kotzar
,
G. M.
,
Brown
,
R. H.
,
Heiple
,
K. G.
,
Goldberg
,
V. M.
,
Heiple
,
K. G.
, Jr.
,
Berilla
,
J.
, and
Burstein
,
A. H.
, 1988, “
Telemetric Force Measurements Across the Hip After Total Arthroplasty
,”
J. Bone Jt. Surg., Am. Vol.
0021-9355,
70-A
(
1
), pp.
45
50
.
9.
Anderson
,
F. C.
, and
Pandy
,
M. G.
, 2001, “
Dynamic Optimization of Human Walking
,”
ASME J. Biomech. Eng.
0148-0731,
123
, pp.
381
390
.
10.
Andriacchi
,
T. P.
,
Natarajan
,
R. N.
, and
Hurwitz
,
D. E.
, 1997, “
Musculoskeletal Dynamics, Locomotion, and Clinical Applications
,”
In Basic Orthopaedic Biomechanics
,
V. C.
Mow
and
W. C.
Hayes
, eds., 2nd ed.,
Lippincott-Raven
,
Philadelphia
, pp.
37
68
.
11.
Komistek
,
R. D.
,
Kane
,
T. R.
,
Mahfouz
,
M.
,
Ochoa
,
J. A.
, and
Dennis
,
D. A.
, 2005, “
Knee Mechanics: A Review of Past and Present Techniques to Determine In Vivo Loads
,”
J. Biomech.
0021-9290,
38
, pp.
215
228
.
12.
Miller
,
R. K.
,
Murray
,
D. W.
,
Gill
,
H. S.
,
O’Connor
,
J. J.
, and
Goodfellow
,
J. W.
, 1997, “
In Vitro Patellofemoral Joint Force Determined by a Non-Invasive Technique
,”
Clinical Biomechanics
,
12
(
1
), pp.
l
7
.
13.
Miller
,
R. K.
,
Goodfellow
,
J. W.
,
Murray
,
D. W.
,
Gill
,
H. S.
, and
O’Connor
,
J. J.
, 1998, “
In Vitro Measurement of Patellofemoral Force After Three Types of Knee Replacement
,”
J. Bone Jt. Surg., Br. Vol.
0301-620X,
80-b
(
5
), pp.
900
906
.
14.
Benjamin
,
J. B.
,
Szivek
,
J. A.
,
Hammond
,
A. S.
,
Kubchandhani
,
Z.
, and
Matthews
,
A. I.
, 1998, “
Contact Areas and Pressures Between Native Patellae and Prosthetic Femoral Components
,”
J. Arthroplasty
0883-5403,
13
(
6
), pp.
693
698
.
15.
Tanzer
,
M.
,
McLean
,
C. A.
,
Laxer
,
E.
,
Casey
,
J.
, and
Ahmed
,
A. M.
, 2001, “
Effect of Femoral Component Designs on the Contact and Tracking Characteristics of the Unresurfaced Patella in Total Knee Arthroplasty
,”
Can. J. Surg.
0008-428X,
44
(
2
), pp.
127
313
.
16.
Kaufman
,
K. R.
,
Kovacevic
,
N.
,
Irby
,
S. E.
, and
Colwell
,
C. W.
, 1996, “
Instrumented Implant for Measuring Tibiofemoral Forces
,”
J. Biomech.
0021-9290,
29
(
5
), pp.
667
671
.
17.
Rydell
,
N. W.
, 1966, “
Forces Acting in the Femoral Head Prosthesis
,”
Acta Orthop. Scand.
0001-6470,
37
, pp.
1
132
.
18.
Szivek
,
J. A.
,
Johnson
,
E. M.
, and
Magee
,
F. P.
, 1992, “
An In Vivo Strain Analysis of the Greyhound Femoral Diaphysis
,”
J. Invest Surg.
0894-1939,
5
, pp.
91
108
.
19.
Szivek
,
J. A.
,
Johnson
,
E. M.
,
Magee
,
F. P.
,
Emmanual
,
J.
,
Poser
,
R. D.
, and
Koeneman
,
J. B.
, 1994, “
Bone Remodeling and In Vivo Strain Analysis of Intact and Implanted Greyhound Proximal Femora
,”
J. Invest Surg.
0894-1939,
7
(
3
), pp.
213
233
.
20.
Szivek
,
J. A.
,
Anderson
,
P. L.
, and
DeYoung
,
D.
, 1997, “
In Vivo Strain Measurements Collected Using Calcium Phosphate Ceramic Bonded Strain Gauges
,”
J. Invest Surg.
0894-1939,
10
(
5
), pp.
263
273
.
21.
Rabkin
,
B. A.
,
Szivek
,
J. A.
,
Schonfeld
,
J.
, and
Halloran
,
B. P.
, 2001, “
Long-Term Measurement of Bone Strain In Vivo: The Rat Tibia
,”
J. Biomed. Mater. Res.
0021-9304,
58
(
3
), pp.
277
281
.
22.
Szivek
,
J. A.
,
Roberto
,
R. F.
, and
Margolis
,
D. S.
, 2005, “
In Vivo Strain Measurements From Hardware and Lamina During Spine Fusion
,”
J. Biomed. Mater. Res., Part B: Appl. Biomater.
1552-4973,
75
(
2
), pp.
243
250
.
23.
Szivek
,
J. A.
,
Roberto
,
R. F.
,
Slack
,
J. M.
, and
Majeed
,
B. S.
, 2002, “
An Implantable Strain Measurement System Designed to Detect Spine Fusion
,”
Spine
0362-2436,
27
(
5
), pp.
487
497
.
24.
Graichen
,
F.
,
Bergmann
,
G.
, and
Rohlmann
,
A.
, 1999, “
Hip Endoprosthesis for In Vivo Measurement of Joint Force and Temperature
,”
J. Biomech.
0021-9290,
32
(
10
), pp.
1113
1117
.
25.
Maan
,
H. S.
,
Szivek
,
J. A.
, and
Benjamin
,
J. B.
, 1999, “
Development of a Knee Telemetry Data Capture and Feedback System
,”
J. Investig. Med.
1081-5589,
47
(
2
), p.
40A
.
26.
Morris
,
B. A.
,
D’Lima
,
D. D.
,
Slamin
,
J. E.
,
Kovacevic
,
N.
,
Arms
,
S. W.
,
Townsend
,
C.
, and
Colwell
,
C. W.
, Jr.
, 2001, “
e-Knee: Evolution of the Electronic Knee Prosthesis: Telemetry Technology Development
,”
J. Bone Jt. Surg., Am. Vol.
0021-9355,
83-A
, pp.
62
66
.
27.
D’Lima
,
D. D.
,
Townsend
,
C. P.
,
Arms
,
S. W.
,
Morris
,
B. A.
, and
Colwell
,
C. W.
, Jr.
, 2005, “
An Implantable Telemetry Device to Measure Intra-Articular Tibial Forces
,”
J. Biomech.
0021-9290,
38
(
2
), pp.
299
304
.
28.
Szivek
,
J. A.
,
Bliss
,
C. L.
,
Geffre
,
C. P.
,
Margolis
,
D. S.
,
DeYoung
,
D. W.
,
Ruth
,
J. T.
,
Schnepp
,
A. B.
,
Tellis
,
B. C.
, and
Vaidyanathan
,
R. K.
, 2006, “
An Instrumented Scaffold Can Monitor Loading in the Knee Joint
,”
J. Biomed. Mater. Res., Part B: Appl. Biomater.
1552-4973,
79B
(
2
), pp.
218
228
.
29.
Geffre
,
C. P.
,
Bliss
,
C. L.
,
Szivek
,
J. A.
,
DeYoung
,
D. W.
,
Ruth
,
J. T.
, and
Margolis
,
D. S.
, 2008, “
Sensate Scaffolds Coupled to Telemetry Can Monitor In Vivo Loading From Within a Joint Over Extended Periods of Time
,”
J. Biomed. Mater. Res., Part B: Appl. Biomater.
1552-4973,
84B
(
1
), pp.
263
270
.
30.
Lin
,
Y. H.
,
Jan
,
I. C.
,
Ko
,
P. C.
,
Chen
,
Y. Y.
,
Wong
,
J. M.
, and
Jan
,
G. J.
, 2004, “
A Wireless PDA-Based Physiological Monitoring System for Patient Transport
,”
IEEE Trans. Inf. Technol. Biomed.
1089-7771,
8
(
4
), pp.
439
447
.
31.
Tellis
,
B. C.
,
Szivek
,
J. A.
,
Bliss
,
C. L.
,
Margolis
,
D. S.
,
Vaidyanathan
,
R. K.
, and
Calvert
,
P.
, 2008, “
Trabecular Scaffolds Created Using Micro CT Guided Fused Deposition Modelling
,”
Mater. Sci. Eng., C
0928-4931,
28/1
, pp.
171
178
.
32.
Maan
,
H.
, and
Szivek
,
J. A.
, 1998, “
Development of Data Capture Software for an Artificial Knee With Sensors and Telemetry
,”
Rehabilitation R&D Progress Reports
, Sec. 10, Article 171.
33.
2005,
Labview Fundamentals
, National Instruments, Austin, TX.
35.
Hinton
,
R.
,
Moody
,
R. L.
,
Davis
,
A. W.
, and
Thomas
,
S. F.
, 2002, “
Osteoarthritis: Diagnosis and Therapeutic Considerations
,”
Am. Fam. Physician
0002-838X,
65
(
5
), pp.
841
848
.
36.
Wise
,
C.
, 2004,
In Osteoarthritis
,
D. C.
Dale
and
D. D.
Federman
, eds.,
WebMD
,
New York
, Chap. 10, Sec. 15.
37.
2002, “
Centers for Disease Control and Prevention, Prevalence of Self-Reported Arthritis or Chronic Joint Symptoms Among Adults—United States, 2001
,”
MMWR Morb Mortal Wkly Rep.
0149-2195,
51
(
42
), pp.
948
950
.
38.
Redman
,
S. N.
,
Oldfield
,
S. F.
, and
Archer
,
C. W.
, 2005, “
Current Strategies for Articular Cartilage Repair
,”
Dev. Cell
1534-5807,
9
, pp.
23
32
.
39.
Perry
,
J.
,
Antonelli
,
D.
, and
Ford
,
W.
, 1975, “
Analysis of Knee-Joint Forces During Flexed-Knee Stance
,”
J. Bone Jt. Surg., Am. Vol.
0021-9355,
57
, pp.
961
967
.
40.
Taylor
,
S. J.
,
Walker
,
P. S.
,
Perry
,
J. S.
,
Cannon
,
S. R.
, and
Woledge
,
R.
, 1998, “
The Forces in the Distal Femur and the Knee During Walking and Other Activities Measured by Telemetry
,”
J. Arthroplasty
0883-5403,
13
, pp.
428
437
.
41.
Heinlein
,
B.
,
Graichen
,
F.
,
Bender
,
A.
,
Rohlmann
,
A.
, and
Bergmann
,
G.
, 2007, “
Design, Calibration and Pre-Clinical Testing of an Instrumented Tibial Tray
,”
J. Biomech.
0021-9290,
40
, pp.
S4
S10
.
42.
D’Lima
,
D. D.
,
Patila
,
S.
,
Steklova
,
N.
,
Chienb
,
S.
, and
Colwell
,
C. W.
, Jr.
, 2007, “
In Vivo Knee Moments and Shear After Total Knee Arthroplasty
,”
J. Biomech.
0021-9290,
40
, pp.
S11
S17
.
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