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J. D. Humphrey
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Proceedings Papers

Elastodynamics of Intracranial Saccular Aneurysms

A. D. Shah, A. Dimas, J. D. Humphrey
Proc. ASME. IMECE97, Advances in Bioengineering, 97-98, November 16–21, 1997
Publisher: American Society of Mechanical Engineers
Paper No: IMECE1997-0246
https://doi.org/10.1115/IMECE1997-0246
View Paper titled, Elastodynamics of Intracranial Saccular Aneurysms
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Topics: Aneurysms, Elastodynamics, Membranes, Pseudoelasticity, Shapes, Stiffness
Journal Articles

Computer-Controlled Biaxial Bioreactor for Investigating Cell-Mediated Homeostasis in Tissue Equivalents

J. F. Eichinger, D. Paukner, J. M. Szafron, R. C. Aydin, J. D. Humphrey, C. J. Cyron
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2020, 142(7): 071011.
Paper No: BIO-19-1337
https://doi.org/10.1115/1.4046201
Published Online: April 8, 2020
View Article titled, Computer-Controlled Biaxial Bioreactor for Investigating Cell-Mediated Homeostasis in Tissue Equivalents
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Topics: Biological tissues, Bioreactors, Computers, Density, Stress, Strips, Relaxation (Physics), Tension
Includes: Supplementary data
Journal Articles

Arterial Stiffness: Different Metrics, Different Meanings

B. Spronck, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091004.
Paper No: BIO-19-1040
https://doi.org/10.1115/1.4043486
Published Online: August 2, 2019
View Article titled, Arterial Stiffness: Different Metrics, Different Meanings
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Topics: Atomic force microscopy, Stiffness, Stress, Pressure, Elasticity, Waves, Deformation, Testing
Journal Articles

Journal of Biomechanical Engineering: Legacy Paper 2017

J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. February 2018, 140(2): 020206.
Paper No: BIO-17-1485
https://doi.org/10.1115/1.4038593
Published Online: January 18, 2018
View Article titled, Journal of Biomechanical Engineering: Legacy Paper 2017
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Topics: Biomechanical engineering, Biomechanics, Residual stresses, Stress
Journal Articles

Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?

C. Bellini, A. W. Caulk, G. Li, G. Tellides, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2017, 139(4): 044501.
Paper No: BIO-16-1400
https://doi.org/10.1115/1.4035551
Published Online: January 31, 2017
View Article titled, Biomechanical Phenotyping of the Murine Aorta: What Is the Best Control?
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Topics: Aorta, Biomechanics, Stiffness, Vessels
Journal Articles

Reduced Biaxial Contractility in the Descending Thoracic Aorta of Fibulin-5 Deficient Mice

S.-I. Murtada, J. Ferruzzi, H. Yanagisawa, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2016, 138(5): 051008.
Paper No: BIO-15-1474
https://doi.org/10.1115/1.4032938
Published Online: March 30, 2016
View Article titled, Reduced Biaxial Contractility in the Descending Thoracic Aorta of Fibulin-5 Deficient Mice
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Topics: Aorta, Pressure, Stress, Vessels, Wall thickness, Surface mount components, Muscle, Testing, Stiffness, Biomechanics
Journal Articles

Local Versus Global Mechanical Effects of Intramural Swelling in Carotid Arteries

T. A. Sorrentino, L. Fourman, J. Ferruzzi, K. S. Miller, J. D. Humphrey, S. Roccabianca
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2015, 137(4): 041008.
Paper No: BIO-14-1330
https://doi.org/10.1115/1.4029303
Published Online: April 1, 2015
View Article titled, Local Versus Global Mechanical Effects of Intramural Swelling in Carotid Arteries
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Topics: Carotid arteries, Mechanical properties, Pressure, Stress, Vessels, Deformation, Testing, Mechanical testing, Fibers, Stiffness
Journal Articles

Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin-5 Deficiency Independent of Sex

J. Ferruzzi, M. R. Bersi, S. Uman, H. Yanagisawa, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2015, 137(3): 031007.
Paper No: BIO-14-1111
https://doi.org/10.1115/1.4029431
Published Online: March 1, 2015
View Article titled, Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin-5 Deficiency Independent of Sex
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Topics: Energy storage, Fibers, Pressure, Stiffness, Stress, Aorta, Energy dissipation, Blood, Biomechanics
Proceedings Papers

Importance of Axial Stress in Arterial Growth and Remodeling

J. D. Humphrey
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 951-952, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192070
https://doi.org/10.1115/SBC2008-192070
View Paper titled, Importance of Axial Stress in Arterial Growth and Remodeling
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Topics: Biology, Blood, Blood flow, Endothelial cells, Flow (Dynamics), Hemodynamics, Hoop stress, Muscle, Pressure, Proteins
Proceedings Papers

Constrained Mixture Models of Arterial Homeostasis and Adaptation

J. D. Humphrey
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 155, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-204922
https://doi.org/10.1115/SBC2009-204922
View Paper titled, Constrained Mixture Models of Arterial Homeostasis and Adaptation
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Topics: Aneurysms, Blood flow, Constitutive equations, Diseases, Geometry, Kinematics, Mechanical behavior, Mechanical properties, Mechanobiology, Pressure
Proceedings Papers

On the Mechanical Behavior of Healthy and Aneurysmal Abdominal Aorta

J. Ferruzzi, M. S. Enevoldsen, J. D. Humphrey
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 705-706, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53852
https://doi.org/10.1115/SBC2011-53852
View Paper titled, On the Mechanical Behavior of Healthy and Aneurysmal Abdominal Aorta
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Topics: Aorta, Mechanical behavior, Fibers, Aneurysms, Biological tissues, Biomechanics, Failure, Isotropy, Muscle, Rupture
Proceedings Papers

Roles of Elastin, Muscle Contractility and Collagenous Stiffening in Aortic Aging: A Thick-Walled Multi-Layered Model

A. Valentín, J. D. Humphrey, G. A. Holzapfel
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 595-596, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53392
https://doi.org/10.1115/SBC2011-53392
View Paper titled, Roles of Elastin, Muscle Contractility and Collagenous Stiffening in Aortic Aging: A Thick-Walled Multi-Layered Model
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Topics: Muscle, Mechanical properties, Aneurysms, Aorta, Cardiovascular system, Diseases, Geometry, Stress
Journal Articles

Biochemomechanics of Intraluminal Thrombus in Abdominal Aortic Aneurysms

J. S. Wilson, L. Virag, P. Di Achille, I. Karšaj, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021011.
Paper No: BIO-12-1552
https://doi.org/10.1115/1.4023437
Published Online: February 7, 2013
View Article titled, Biochemomechanics of Intraluminal Thrombus in Abdominal Aortic Aneurysms
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Topics: Aneurysms, Thrombosis, Hemodynamics, Modeling
Journal Articles

Differential Passive and Active Biaxial Mechanical Behaviors of Muscular and Elastic Arteries: Basilar Versus Common Carotid

H. P. Wagner, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2011, 133(5): 051009.
https://doi.org/10.1115/1.4003873
Published Online: May 17, 2011
View Article titled, Differential Passive and Active Biaxial Mechanical Behaviors of Muscular and Elastic Arteries: Basilar Versus Common Carotid
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Topics: Biomechanics, Carotid arteries, Constitutive equations, Fibers, Muscle, Stress, Vessels, Testing, Diseases, Pressure
Journal Articles

Parameter Sensitivity Study of a Constrained Mixture Model of Arterial Growth and Remodeling

A. Valentín, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2009, 131(10): 101006.
https://doi.org/10.1115/1.3192144
Published Online: September 2, 2009
View Article titled, Parameter Sensitivity Study of a Constrained Mixture Model of Arterial Growth and Remodeling
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Topics: Flow (Dynamics), Muscle, Pressure, Stress, Shear stress, Shear (Mechanics), Mass production, Biomechanics, Wall thickness
Journal Articles

Altered Multiaxial Mechanical Properties of the Porcine Anterior Lens Capsule Cultured in High Glucose

R. M. Pedrigi, E. Staff, G. David, S. Glenn, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2007, 129(1): 121–125.
https://doi.org/10.1115/1.2401192
Published Online: July 26, 2006
View Article titled, Altered Multiaxial Mechanical Properties of the Porcine Anterior Lens Capsule Cultured in High Glucose
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Topics: Biological tissues, Biomechanics, Diabetes, Glucose, Lenses (Optics), Mechanical properties, Proteins, Anisotropy, Pressure, Finite element analysis
Journal Articles

Regional Multiaxial Mechanical Properties of the Porcine Anterior Lens Capsule

G. David, R. M. Pedrigi, M. R. Heistand, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2007, 129(1): 97–104.
https://doi.org/10.1115/1.2401188
Published Online: June 26, 2006
View Article titled, Regional Multiaxial Mechanical Properties of the Porcine Anterior Lens Capsule
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Topics: Biomechanics, Finite element methods, Lenses (Optics), Mechanical properties, Poles (Building), Stress, Finite element analysis, Stiffness, Anisotropy
Journal Articles

A Theoretical Model of Enlarging Intracranial Fusiform Aneurysms

S. Baek, K. R. Rajagopal, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2006, 128(1): 142–149.
https://doi.org/10.1115/1.2132374
Published Online: September 27, 2005
View Article titled, A Theoretical Model of Enlarging Intracranial Fusiform Aneurysms
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Topics: Aneurysms, Stress, Fibers, Biomechanics
Journal Articles

A Multiaxial Computer-Controlled Organ Culture and Biomechanical Device for Mouse Carotid Arteries

R. L. Gleason, S. P. Gray, E. Wilson, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2004, 126(6): 787–795.
https://doi.org/10.1115/1.1824130
Published Online: February 4, 2005
View Article titled, A Multiaxial Computer-Controlled Organ Culture and Biomechanical Device for Mouse Carotid Arteries
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Topics: Biomechanics, Carotid arteries, Computers, Flow (Dynamics), Mechanical testing, Pressure, Stress, Vessels, Testing, Calibration
Journal Articles

Heat-Induced Changes in the Finite Strain Viscoelastic Behavior of a Collaagenous Tissue

S. Baek, P. B. Wells, K. R. Rajagopal, J. D. Humphrey
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. August 2005, 127(4): 580–586.
https://doi.org/10.1115/1.1934222
Published Online: January 14, 2005
View Article titled, Heat-Induced Changes in the Finite Strain Viscoelastic Behavior of a Collaagenous Tissue
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Topics: Biological tissues, Relaxation (Physics), Stress, Viscoelasticity, Temperature, Damage, Heat